KiOnutrime-CsG® – The proven weight management tool

– by KitoZyme (2015)


KiOnutrime-CsG® is a natural ingredient that is scientifically proven to help people to manage their weight. In a recently completed clinical trial1 it was found that overweight subjects consuming KiOnutrime-CsG® lost an average of 3.2kg over three months, compared with a small weight increase on average in the control group.

Produced by KitoZyme at its manufacturing facility in Belgium, KiOnutrime-CsG® works by safely preventing some of the fat in food from being absorbed by the body. It is a cationic (positively charged) biopolymer that binds with anionic (negatively charged) molecules such as fats and fatty acids and obstructs the emulsification and absorption of cholesterol.

Taken just a few minutes before a meal, KiOnutrime-CsG® will bind dietary fat in the stomach to form a gel that is later excreted naturally without being absorbed. A previous study carried out using a lab-based model of the human gut showed that KiOnutrime-CsG® can bind 42% of the fats ingested in a typical meal2 , as shown below in Figure 1. The latest human study, which is awaiting publication in a peer-reviewed journal, confirms that this mechanism has a statistically significant impact on weight loss in healthy overweight people.

For the full study, click here.


Single-blind, placebo controlled randomised clinical study of chitosan for body weight reduction

– by V. R. Trivedi et al. (2016)


Chitosan is a dietary fiber that acts by reducing absorption and thus as a means for controlling weight. Weight loss clinical trial outcomes, however, have contradictory results regarding its efficacy. The primary objective of the present study was to evaluate the efficacy and safety of chitosan from the fungal origin in the treatment of excess weight in the absence of dietary restrictions.

For the full study, click here.